KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPP2
All Species:
25.76
Human Site:
T524
Identified Species:
43.59
UniProt:
P29144
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29144
NP_003282.2
1249
138350
T524
F
A
N
K
L
G
F
T
V
T
V
G
N
N
R
Chimpanzee
Pan troglodytes
XP_001151602
1249
138350
T524
F
A
N
K
L
G
F
T
V
T
V
G
N
N
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64514
1262
139860
T524
F
A
N
R
L
G
F
T
V
T
V
G
N
N
R
Rat
Rattus norvegicus
Q64560
1249
138274
T524
F
A
N
R
L
G
F
T
V
T
V
G
N
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513544
1367
152093
T629
F
T
S
K
I
G
F
T
V
T
V
G
N
N
R
Chicken
Gallus gallus
XP_425591
1248
138209
T523
F
T
S
N
I
G
F
T
I
T
V
G
S
N
R
Frog
Xenopus laevis
NP_001085380
1261
139671
T524
L
F
S
K
I
G
F
T
I
T
V
G
N
N
R
Zebra Danio
Brachydanio rerio
XP_693179
595
63935
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V6K1
1441
158719
V628
M
L
R
F
S
V
R
V
G
N
N
A
D
K
G
Honey Bee
Apis mellifera
XP_395521
1450
161968
C531
D
V
R
F
T
I
N
C
G
P
N
N
A
K
G
Nematode Worm
Caenorhab. elegans
Q09541
1374
151070
L574
N
K
V
F
P
P
R
L
T
H
F
E
I
N
V
Sea Urchin
Strong. purpuratus
XP_788834
1215
133209
V522
C
D
C
P
S
R
N
V
K
F
N
V
S
F
D
Poplar Tree
Populus trichocarpa
XP_002318216
1299
143140
G561
E
I
K
V
N
Q
S
G
K
T
T
P
T
S
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_193817
1380
152349
G641
Q
I
K
V
N
L
S
G
K
T
I
P
T
S
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
N.A.
N.A.
95.3
96.8
N.A.
81.2
86
80.4
37.7
N.A.
34
41.3
35
54.7
Protein Similarity:
100
99.7
N.A.
N.A.
N.A.
97.4
98.7
N.A.
86.6
94.6
91.3
43.1
N.A.
53
59.2
53.4
71.6
P-Site Identity:
100
100
N.A.
N.A.
N.A.
93.3
93.3
N.A.
80
60
66.6
0
N.A.
0
0
6.6
0
P-Site Similarity:
100
100
N.A.
N.A.
N.A.
100
100
N.A.
93.3
86.6
86.6
0
N.A.
6.6
0
6.6
6.6
Percent
Protein Identity:
38
N.A.
N.A.
37.4
N.A.
N.A.
Protein Similarity:
56.9
N.A.
N.A.
54.1
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
29
0
0
0
0
0
0
0
0
0
8
8
0
0
% A
% Cys:
8
0
8
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
0
0
0
0
0
0
0
0
8
0
8
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% E
% Phe:
43
8
0
22
0
0
50
0
0
8
8
0
0
8
0
% F
% Gly:
0
0
0
0
0
50
0
15
15
0
0
50
0
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
15
0
0
22
8
0
0
15
0
8
0
8
0
0
% I
% Lys:
0
8
15
29
0
0
0
0
22
0
0
0
0
15
0
% K
% Leu:
8
8
0
0
29
8
0
8
0
0
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
29
8
15
0
15
0
0
8
22
8
43
58
0
% N
% Pro:
0
0
0
8
8
8
0
0
0
8
0
15
0
0
0
% P
% Gln:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
15
15
0
8
15
0
0
0
0
0
0
0
65
% R
% Ser:
0
0
22
0
15
0
15
0
0
0
0
0
15
15
0
% S
% Thr:
0
15
0
0
8
0
0
50
8
65
8
0
15
0
0
% T
% Val:
0
8
8
15
0
8
0
15
36
0
50
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _